Irinotecan combined with bolus fluorouracil, continuous infusion fluorouracil, and high-dose leucovorin every two weeks (LV5FU2 regimen): a clinical dose-finding and pharmacokinetic study in patients with pretreated metastatic colorectal cancer.
第一作者:
M,Ducreux
第一单位:
Institut Gustave Roussy, Villejuif, France.
作者:
主题词
成年人(Adult);老年人(Aged);解毒药(Antidotes);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);喜树碱(Camptothecin);结肠肿瘤(Colonic Neoplasms);腹泻(Diarrhea);用药计划表(Drug Administration Schedule);女(雌)性(Female);氟尿嘧啶(Fluorouracil);人类(Humans);醛氢叶酸(Leucovorin);男(雄)性(Male);中年人(Middle Aged);中性粒细胞减少(Neutropenia);直肠肿瘤(Rectal Neoplasms)
DOI
10.1200/JCO.1999.17.9.2901
PMID
10561369
发布时间
2022-03-30
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