Heterogeneous apoptotic responses of prostate cancer cell lines identify an association between sensitivity to staurosporine-induced apoptosis, expression of Bcl-2 family members, and caspase activation.
第一作者:
M,Marcelli
第一单位:
Departments of Medicine, Molecular and Cellular Biology, Veterans Administration Medical Center and Baylor College of Medicine, Houston, Texas 77030, USA. marcelli@bcm.tmc.edu
作者:
主题词
细胞凋亡(Apoptosis);凋亡调节蛋白质类(Apoptosis Regulatory Proteins);生物转运(Biological Transport);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);半胱氨酸天冬氨酸蛋白酶7(Caspase 7);半胱氨酸天冬氨酸蛋白酶(Caspases);催化作用(Catalysis);细胞存活(Cell Survival);细胞色素c组(Cytochrome c Group);胞质溶胶(Cytosol);DNA碎片裂(DNA Fragmentation);酶激活(Enzyme Activation);酶抑制剂(Enzyme Inhibitors);人类(Humans);原位缺口末端标记(In Situ Nick-End Labeling);细胞内膜(Intracellular Membranes);男(雄)性(Male);线粒体(Mitochondria);坏死(Necrosis);聚ADP核糖聚合酶类(Poly(ADP-ribose) Polymerases);前列腺肿瘤(Prostatic Neoplasms);蛋白质类(Proteins);原癌基因蛋白质类(Proto-Oncogene Proteins);原癌基因蛋白质c-bcl-2(Proto-Oncogene Proteins c-bcl-2);星状孢子素(Staurosporine);拓扑异构酶II抑制剂(Topoisomerase II Inhibitors);肿瘤细胞, 培养的(Tumor Cells, Cultured);bcl-2相关X蛋白质(bcl-2-Associated X Protein)
DOI
10.1002/(sici)1097-0045(20000301)42:4<260::aid-pros3>3.0.co;2-0
PMID
10679755
发布时间
2021-12-03
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The Prostate
260-73页
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