Bis(phenazine-1-carboxamides): structure-activity relationships for a new class of dual topoisomerase I/II-directed anticancer drugs.
第一作者:
J A,Spicer
第一单位:
Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1000, New Zealand.
作者:
医学主题词
酰胺类(Amides);动物(Animals);抗肿瘤药(Antineoplastic Agents);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);酶抑制剂(Enzyme Inhibitors);人类(Humans);小鼠(Mice);肿瘤移植(Neoplasm Transplantation);吩嗪类(Phenazines);构效关系(Structure-Activity Relationship);拓扑异构酶I抑制剂(Topoisomerase I Inhibitors);拓扑异构酶II抑制剂(Topoisomerase II Inhibitors);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1021/jm990423f
PMID
10753472
发布时间
2019-07-09
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