Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase.
第一作者:
Philip L,Cohen
第一单位:
Department of Medicine, Division of Rheumatology, University of Pennsylvania, and Philadelphia Veterans Affairs Medical Center, Philadelphia, PA 19104, USA. philipco@mail.med.upenn.edu
作者:
主题词
动物(Animals);细胞凋亡(Apoptosis);自身抗体(Autoantibodies);自身免疫(Autoimmunity);B-淋巴细胞(B-Lymphocytes);心磷脂质类(Cardiolipins);染色质(Chromatin);DNA(DNA);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);荧光染料(Fluorescent Dyes);肾小球系膜(Glomerular Mesangium);免疫球蛋白G(Immunoglobulin G);红斑狼疮, 系统性(Lupus Erythematosus, Systemic);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 突变型(Mice, Mutant Strains);吞噬作用(Phagocytosis);蛋白酪氨酸激酶类(Protein-Tyrosine Kinases);蛋白尿(Proteinuria);原癌基因蛋白质类(Proto-Oncogene Proteins);受体蛋白质酪氨酸激酶类(Receptor Protein-Tyrosine Kinases);类风湿因子(Rheumatoid Factor);若丹明类(Rhodamines)
DOI
10.1084/jem.20012094
PMID
12093878
发布时间
2022-02-27
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