Crystal structure of the heterodimeric complex of LXRalpha and RXRbeta ligand-binding domains in a fully agonistic conformation.
第一作者:
Stefan,Svensson
第一单位:
Department of Structural Chemistry, Biovitrum AB, Lindhagensgatan 133, SE-112 76 Stockholm, Sweden. stefan.j.svensson@biovitrum.com
作者:
主题词
碱基序列(Base Sequence);结合部位(Binding Sites);克隆, 分子(Cloning, Molecular);结晶学, X线(Crystallography, X-Ray);DNA引物(DNA Primers);DNA结合蛋白质类(DNA-Binding Proteins);二聚作用(Dimerization);大肠杆菌(Escherichia coli);配体(Ligands);模型, 分子(Models, Molecular);孤儿核受体(Orphan Nuclear Receptors);肽碎片(Peptide Fragments);聚合酶链反应(Polymerase Chain Reaction);蛋白质构象(Protein Conformation);受体, 胞质和核(Receptors, Cytoplasmic and Nuclear);重组蛋白质类(Recombinant Proteins)
DOI
10.1093/emboj/cdg456
PMID
12970175
发布时间
2018-12-20
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The EMBO journal
4625-33页
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