The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum.
第一作者:
Y,Kashman
第一单位:
Laboratory of Drug Discovery Research and Development, Frederick Cancer Research and Development Center (NCI-FCRDC), Maryland 21702-1201.
作者:
主题词
抗病毒药(Antiviral Agents);色谱法, 液相(Chromatography, Liquid);香豆素类(Coumarins);致细胞病变, 病毒(Cytopathogenic Effect, Viral);抗药性, 微生物(Drug Resistance, Microbial);HIV逆转录酶(HIV Reverse Transcriptase);HIV-1(HIV-1);HIV-2(HIV-2);人类(Humans);水解作用(Hydrolysis);磁共振波谱学(Magnetic Resonance Spectroscopy);吡喃香豆素类(Pyranocoumarins);逆转录酶抑制剂(Reverse Transcriptase Inhibitors);构效关系(Structure-Activity Relationship);树(Trees);肿瘤细胞, 培养的(Tumor Cells, Cultured);病毒复制(Virus Replication)
DOI
10.1021/jm00093a004
PMID
1379639
发布时间
2019-07-09
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