A microscale in vitro physiological model of the liver: predictive screens for drug metabolism and enzyme induction.
第一作者:
A,Sivaraman
第一单位:
Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
作者:
主题词
动物(Animals);生物反应器(Bioreactors);印迹法, 蛋白质(Blotting, Western);细胞培养技术(Cell Culture Techniques);细胞色素P450酶系统(Cytochrome P-450 Enzyme System);基因表达谱(Gene Expression Profiling);肝细胞(Hepatocytes);肝(Liver);男(雄)性(Male);模型, 生物学(Models, Biological);大鼠(Rats);大鼠, 近交F344(Rats, Inbred F344);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);转录因子(Transcription Factors)
DOI
10.2174/138920005774832632
PMID
16379670
发布时间
2019-10-26
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Current drug metabolism
569-91页
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