A monoclonal antibody against CD148, a receptor-like tyrosine phosphatase, inhibits endothelial-cell growth and angiogenesis.
第一作者:
Takamune,Takahashi
第一单位:
Vanderbilt University Medical Center, Division of Nephrology, Nashville, TN 37232, USA. takamune.takahashi@vanderbilt.edu
作者:
主题词
动物(Animals);抗体, 单克隆(Antibodies, Monoclonal);CHO细胞(CHO Cells);角膜(Cornea);仓鼠亚科(Cricetinae);仓鼠属(Cricetulus);内皮细胞(Endothelial Cells);酶抑制剂(Enzyme Inhibitors);G1期(G1 Phase);人类(Humans);炎症(Inflammation);丝裂原活化蛋白激酶1(Mitogen-Activated Protein Kinase 1);丝裂原活化蛋白激酶3(Mitogen-Activated Protein Kinase 3);肿瘤(Neoplasms);新生血管化, 病理性(Neovascularization, Pathologic);磷酰化(Phosphorylation);蛋白质加工, 转译后(Protein Processing, Post-Translational);蛋白质结构, 三级(Protein Structure, Tertiary);蛋白质酪氨酸磷酸酶类(Protein Tyrosine Phosphatases);原癌基因蛋白质c-met(Proto-Oncogene Proteins c-met);受体样蛋白质酪氨酸磷酸酶类, 3类(Receptor-Like Protein Tyrosine Phosphatases, Class 3)
DOI
10.1182/blood-2005-10-4296
PMID
16597593
发布时间
2021-02-06
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Blood
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