Reactive oxygen species stabilize hypoxia-inducible factor-1 alpha protein and stimulate transcriptional activity via AMP-activated protein kinase in DU145 human prostate cancer cells.
第一作者:
Seung-Nam,Jung
第一单位:
Department of Biochemistry and Molecular Biology, Kyung Hee University School of Medicine, Seoul 130-701, Korea.
作者:
主题词
腺苷酸激酶(Adenylate Kinase);癌, 肝细胞(Carcinoma, Hepatocellular);细胞系, 肿瘤(Cell Line, Tumor);结肠肿瘤(Colonic Neoplasms);酶激活(Enzyme Activation);基因转移技术(Gene Transfer Techniques);基因, 报告(Genes, Reporter);基因, myc(Genes, myc);人类(Humans);缺氧诱导因子1, α亚基(Hypoxia-Inducible Factor 1, alpha Subunit);肝肿瘤(Liver Neoplasms);肺肿瘤(Lung Neoplasms);男(雄)性(Male);前列腺肿瘤(Prostatic Neoplasms);RNA, 肿瘤(RNA, Neoplasm);活性氧(Reactive Oxygen Species);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);转录, 遗传(Transcription, Genetic);泛素(Ubiquitin)
DOI
10.1093/carcin/bgn032
PMID
18258605
发布时间
2008-04-02
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Carcinogenesis
713-21页
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