Design, synthesis, and biological evaluation of platensimycin analogues with varying degrees of molecular complexity.
第一作者:
K C,Nicolaou
第一单位:
Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA. kcn@scripps.edu
作者:
医学主题词
金刚烷(Adamantane);酰苯胺类(Anilides);苯胺化合物(Aniline Compounds);抗感染药(Anti-Infective Agents);苯甲醛类(Benzaldehydes);苯甲酸盐类(Benzoates);苯并二恶茂类(Benzodioxoles);环己烯类(Cyclohexenes);药物设计(Drug Design);环氧化合物(Epoxy Compounds);甲氧西林抗药性(Methicillin Resistance);微生物敏感性试验(Microbial Sensitivity Tests);吡喃类(Pyrans);金黄色葡萄球菌(Staphylococcus aureus);构效关系(Structure-Activity Relationship)
DOI
10.1021/ja8044376
PMID
18771264
发布时间
2025-05-29
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