换一批Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease.
第一作者：
Chia-Hsiung,Chen
第一单位：
Townsend Family Laboratories, Department of Psychiatry, Brain Research Center, Graduate Program in Neuroscience, The University of British Columbia, Vancouver, Canada.
作者：
医学主题词
老年人(Aged);老年人, 80以上(Aged, 80 and over);阿尔茨海默病(Alzheimer Disease);淀粉样前体蛋白分泌酶类(Amyloid Precursor Protein Secretases);淀粉样β肽类(Amyloid beta-Peptides);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);消炎药, 非甾类(Anti-Inflammatory Agents, Non-Steroidal);天冬氨酸内肽酶类(Aspartic Acid Endopeptidases);脑(Brain);人类(Humans);启动区, 遗传(Promoter Regions, Genetic);信号传导(Signal Transduction);转录因子RelA(Transcription Factor RelA);转录, 遗传(Transcription, Genetic);肿瘤坏死因子α(Tumor Necrosis Factor-alpha);增量调节(Up-Regulation)
DOI
10.1017/S1461145711000149
PMID
21329555
发布时间
2022-11-09
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