Microsomal cytochrome P450-mediated metabolism of hypaconitine, an active and highly toxic constituent derived from Aconitum species.
第一作者:
Ling,Ye
第一单位:
Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou, Guangdong 510515, China.
作者:
医学主题词
乌头碱(Aconitine);细胞色素P-450 CYP3A(Cytochrome P-450 CYP3A);细胞色素P450酶系统(Cytochrome P-450 Enzyme System);气相色谱-质谱法(Gas Chromatography-Mass Spectrometry);人类(Humans);羟基化(Hydroxylation);微粒体, 肝(Microsomes, Liver)
DOI
10.1016/j.toxlet.2011.04.015
PMID
21550385
发布时间
2018-12-11
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Toxicology letters
81-91页
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