换一批In vitro cellular uptake and dimerization of signal transducer and activator of transcription-3 (STAT3) identify the photosensitizing and imaging-potential of isomeric photosensitizers derived from chlorophyll-a and bacteriochlorophyll-a.
第一作者：
Avinash,Srivatsan
第一单位：
Department of Cell Stress Biology/PDT Center, Molecular Pharmacology and Cancer Therapeutics, Roswell Park Cancer Institute, Buffalo, New York 14263, United States.
作者：
医学主题词
动物(Animals);细菌叶绿素A(Bacteriochlorophyll A);细胞系, 肿瘤(Cell Line, Tumor);叶绿素(Chlorophyll);人类(Humans);碘放射性同位素(Iodine Radioisotopes);异构现象(Isomerism);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);肿瘤移植(Neoplasm Transplantation);肿瘤, 实验性(Neoplasms, Experimental);光敏感药(Photosensitizing Agents);正电子发射断层显像术(Positron-Emission Tomography);蛋白质多聚化(Protein Multimerization);放射性药物(Radiopharmaceuticals);STAT3转录因子(STAT3 Transcription Factor);构效关系(Structure-Activity Relationship);移植, 异种(Transplantation, Heterologous)
DOI
10.1021/jm200805y
PMID
21842893
发布时间
2025-05-29
基金项目
P30 CA016056/CA/NCI NIH HHS/United States
R01 CA127369/CA/NCI NIH HHS/United States
R01CA127369/CA/NCI NIH HHS/United States
P01 CA55791/CA/NCI NIH HHS/United States
CA16056/CA/NCI NIH HHS/United States
P01 CA055791/CA/NCI NIH HHS/United States
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