A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens.
第一作者:
J,Veldscholte
第一单位:
Department of Biochemistry II, Erasmus University Rotterdam, The Netherlands.
作者:
主题词
结合部位(Binding Sites);结合, 竞争性(Binding, Competitive);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);配体(Ligands);男(雄)性(Male);突变(Mutation);前列腺肿瘤(Prostatic Neoplasms);受体, 雄激素(Receptors, Androgen);甾类(Steroids);转染(Transfection);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1016/s0006-291x(05)80067-1
PMID
2260966
发布时间
2019-06-12
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