Ableson kinases negatively regulate invadopodia function and invasion in head and neck squamous cell carcinoma by inhibiting an HB-EGF autocrine loop.
第一作者:
K E,Hayes
第一单位:
Department of Neurobiology and Anatomy, Program in Cancer Cell Biology, Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV, USA.
作者:
主题词
抗肿瘤药(Antineoplastic Agents);苯甲酰胺类(Benzamides);癌, 鳞状细胞(Carcinoma, Squamous Cell);细胞系, 肿瘤(Cell Line, Tumor);细胞外基质(Extracellular Matrix);头颈部肿瘤(Head and Neck Neoplasms);人类(Humans);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);肿瘤侵润(Neoplasm Invasiveness);哌嗪类(Piperazines);蛋白激酶类(Protein Kinases);嘧啶类(Pyrimidines);src族激酶类(src-Family Kinases)
DOI
10.1038/onc.2012.513
PMID
23146907
发布时间
2024-03-23
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Oncogene
4766-77页
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