An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension.
第一作者:
Jongmin,Kim
第一单位:
Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
作者:
主题词
动物(Animals);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);培养基, 条件性(Culture Media, Conditioned);减量调节(Down-Regulation);内皮细胞(Endothelial Cells);成纤维细胞生长因子2(Fibroblast Growth Factor 2);人类(Humans);高血压, 肺性(Hypertension, Pulmonary);胞间信号肽类和蛋白质类(Intercellular Signaling Peptides and Proteins);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);微RNAs(MicroRNAs);肌, 平滑, 血管(Muscle, Smooth, Vascular);肌细胞, 平滑肌(Myocytes, Smooth Muscle);肺动脉(Pulmonary Artery);RNA干扰(RNA Interference);RNA, 小分子干扰(RNA, Small Interfering);大鼠(Rats);受体, 成纤维细胞生长因子, 1型(Receptor, Fibroblast Growth Factor, Type 1);信号传导(Signal Transduction);血管疾病(Vascular Diseases)
DOI
10.1038/nm.3040
PMID
23263626
发布时间
2022-06-09
- 浏览133
Nature medicine
74-82页
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