换一批β-Defensin 2 and 3 promote the uptake of self or CpG DNA, enhance IFN-α production by human plasmacytoid dendritic cells, and promote inflammation.
第一作者：
Poonam,Tewary
第一单位：
Laboratory of Molecular Immunoregulation, Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, Laboratory for Cancer Research, Frederick, MD 21702, USA. tewaryp@mail.nih.gov
作者：
主题词
佐剂, 免疫(Adjuvants, Immunologic);动物(Animals);抗原呈递细胞(Antigen-Presenting Cells);生物转运(Biological Transport);细胞, 培养的(Cells, Cultured);CpG岛(CpG Islands);DNA(DNA);树突细胞(Dendritic Cells);女(雌)性(Female);人类(Humans);亲水和疏水相互作用(Hydrophobic and Hydrophilic Interactions);炎症(Inflammation);干扰素α(Interferon-alpha);干扰素γ(Interferon-gamma);白细胞介素12(Interleukin-12);白细胞介素6(Interleukin-6);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);卵白蛋白(Ovalbumin);Toll样受体9(Toll-Like Receptor 9);β防御素(beta-Defensins)
DOI
10.4049/jimmunol.1201648
PMID
23776172
发布时间
2025-05-29
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