The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time.
第一作者:
Lina,Josefsson
第一单位:
Department of Diagnostics and Vaccinology, Swedish Institute for Infectious Disease Control, 171 82 Solna, Sweden.
作者:
医学主题词
抗逆转录病毒药(Anti-Retroviral Agents);CD4淋巴细胞计数(CD4 Lymphocyte Count);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);带病原状态(Carrier State);DNA, 病毒(DNA, Viral);女(雌)性(Female);基因组, 病毒(Genome, Viral);HIV感染(HIV Infections);HIV-1(HIV-1);人类(Humans);免疫记忆(Immunologic Memory);淋巴组织(Lymphoid Tissue);男(雄)性(Male);突变(Mutation);种系发生(Phylogeny);时间因素(Time Factors)
DOI
10.1073/pnas.1308313110
PMID
24277811
发布时间
2025-05-29
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