Loss of STAT3 in mouse embryonic fibroblasts reveals its Janus-like actions on mitochondrial function and cell viability.
第一作者:
Fouad A,Zouein
第一单位:
Departments of Pharmacology and Toxicology, The University of Mississippi Medical Center, Jackson, MS, USA; School of Medicine and The Mississippi Center for Heart Research, The University of Mississippi Medical Center, Jackson, MS, USA; The Cardiovascular-Renal Research Center, The University of Mississippi Medical Center, Jackson, MS, USA.
作者:
医学主题词
动物(Animals);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);细胞核(Cell Nucleus);细胞呼吸(Cell Respiration);细胞存活(Cell Survival);细胞色素c类(Cytochromes c);细胞保护(Cytoprotection);胚胎, 哺乳动物(Embryo, Mammalian);成纤维细胞(Fibroblasts);人类(Humans);小鼠(Mice);小鼠, 基因敲除(Mice, Knockout);线粒体(Mitochondria);模型, 生物学(Models, Biological);NF-κB(NF-kappa B);蛋白质结合(Protein Binding);活性氧(Reactive Oxygen Species);STAT3转录因子(STAT3 Transcription Factor);信号传导(Signal Transduction);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)
DOI
10.1016/j.cyto.2013.12.006
PMID
24548419
发布时间
2021-10-21
- 浏览63
Cytokine
7-16页
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