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IQGAP1 is important for activation of caspase-1 in macrophages and is targeted by Yersinia pestis type III effector YopM.

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第一作者： Lawton K,Chung

第一单位： Department of Molecular Genetics and Microbiology and Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA.

作者： Lawton K,Chung ^[1] ; Naomi H,Philip ^[2] ; Valentina A,Schmidt ^[3] ; Antonius,Koller ^[4] ; Till,Strowig ^[5] ; Richard A,Flavell ^[5] ; Igor E,Brodsky ^[2] ; James B,Bliska ^[6]

作者单位： Department of Molecular Genetics and Microbiology and Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA. ^[1] Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; ^[2] Department of Medicine, School of Medicine, Stony Brook University, Stony Brook, New York, USA. ^[3] Proteomics Center, School of Medicine, Stony Brook University, Stony Brook, New York, USA; ^[4] Department of Immunobiology and Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, USA. ^[5] Department of Molecular Genetics and Microbiology and Center for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA james.bliska@stonybrook.edu. ^[6]