TLR2 signaling decreases transmission of Streptococcus pneumoniae by limiting bacterial shedding in an infant mouse Influenza A co-infection model.

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作者： Aimee L,Richard ^[1] ; Steven J,Siegel ^[1] ; Jan,Erikson ^[2] ; Jeffrey N,Weiser ^[1]

作者单位： Department of Microbiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America. ^[1] The Wistar Institute, Philadelphia, Pennsylvania, United States of America. ^[2]

主题词动物(Animals);动物, 新生(Animals, Newborn);细菌脱落(Bacterial Shedding);疾病模型, 动物(Disease Models, Animal);流式细胞术(Flow Cytometry);荧光抗体技术(Fluorescent Antibody Technique);流感病毒A型(Influenza A virus);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);正黏病毒科感染(Orthomyxoviridae Infections);肺炎球菌感染(Pneumococcal Infections);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);信号传导(Signal Transduction);肺炎链球菌(Streptococcus pneumoniae);Toll样受体2(Toll-Like Receptor 2)

DOI 10.1371/journal.ppat.1004339

PMID 25166617

发布时间 2021-10-21

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2014年10卷8期

e1004339页

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TLR2 signaling decreases transmission of Streptococcus pneumoniae by limiting bacterial shedding in an infant mouse Influenza A co-infection model.

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PLoS pathogens

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TLR2 signaling decreases transmission of Streptococcus pneumoniae by limiting bacterial shedding in an infant mouse Influenza A co-infection model.

PLoS pathogens

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PLoS pathogens

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