Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation.
作者:
Relja,Popovic [1]
;
Eva,Martinez-Garcia [1]
;
Eugenia G,Giannopoulou [2]
;
Quanwei,Zhang [3]
;
Qingyang,Zhang [3]
;
Teresa,Ezponda [1]
;
Mrinal Y,Shah [1]
;
Yupeng,Zheng [4]
;
Christine M,Will [1]
;
Eliza C,Small [1]
;
Youjia,Hua [1]
;
Marinka,Bulic [1]
;
Yanwen,Jiang [5]
;
Matteo,Carrara [6]
;
Raffaele A,Calogero [6]
;
William L,Kath [7]
;
Neil L,Kelleher [4]
;
Ji-Ping,Wang [3]
;
Olivier,Elemento [5]
;
Jonathan D,Licht [1]
作者单位:
Division of Hematology/Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.
[1]
Arthritis and Tissue Degeneration Program and the David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, New York, United States of America; Biological Sciences Department, New York City College of Technology, City University of New York, Brooklyn, New York, New York, United States of America.
[2]
Department of Statistics, Northwestern University, Evanston, Illinois, United States of America.
[3]
Department of Chemistry and Molecular Biosciences, Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois, United States of America.
[4]
HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine and Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York, United States of America.
[5]
Molecular Biotechnology Center, Department of Biotechnology and Health Sciences, University of Torino, Torino, Italy.
[6]
Department of Engineering Sciences and Applied Mathematics, Northwestern University, Evanston, Illinois, United States of America.
[7]
期刊:
《PLoS genetics》
2014年10卷9期e1004566页
DOI:
10.1371/journal.pgen.1004566
PMID:
25188243
发布时间:
2021-10-21
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