Joint modeling of genetically correlated diseases and functional annotations increases accuracy of polygenic risk prediction.
作者:
Yiming,Hu [1]
;
Qiongshi,Lu [1]
;
Wei,Liu [2]
;
Yuhua,Zhang [3]
;
Mo,Li [1]
;
Hongyu,Zhao [1]
作者单位:
Department of Biostatistics, Yale School of Public Health, New Haven, Connecticut, United States of America.
[1]
Peking University, Beijing, China.
[2]
Shanghai Jiao Tong University, Shanghai, China.
[3]
Program of Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut, United States of America.
[4]
Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America.
[5]
Clinical Epidemiology Research Center (CERC), Veterans Affairs (VA) Cooperative Studies Program, VA Connecticut Healthcare System, West Haven, Connecticut, United States of America.
[6]
期刊:
《PLoS genetics》
2017年13卷6期e1006836页
DOI:
10.1371/journal.pgen.1006836
PMID:
28598966
发布时间:
2022-04-08
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