Lack of human-like extracellular sortilin neuropathology in transgenic Alzheimer's disease model mice and macaques.
第一作者:
Feng-Qin,Zhou
第一单位:
Department of Anatomy and Neurobiology, Central South University School of Basic Medical Science, Changsha, 410013, Hunan, China.
作者:
医学主题词
衔接蛋白质类, 膜泡运输(Adaptor Proteins, Vesicular Transport);阿尔茨海默病(Alzheimer Disease);淀粉样前体蛋白分泌酶类(Amyloid Precursor Protein Secretases);淀粉样β肽类(Amyloid beta-Peptides);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);动物(Animals);天冬氨酸内肽酶类(Aspartic Acid Endopeptidases);脑(Brain);疾病模型, 动物(Disease Models, Animal);细胞外液(Extracellular Fluid);基因表达调控(Gene Expression Regulation);人类(Humans);猕猴(Macaca mulatta);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);突变(Mutation);早老素1(Presenilin-1);tau蛋白质类(tau Proteins)
DOI
10.1186/s13195-018-0370-2
PMID
29690919
发布时间
2024-03-18
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