Galactosylated chitosan triptolide nanoparticles for overcoming hepatocellular carcinoma: Enhanced therapeutic efficacy, low toxicity, and validated network regulatory mechanisms.-论文-万方医学网

第一作者： Yan-Qiong,Zhang

第一单位： Institute of Chinese Materials Medical, China Academy of Chinese Medical Sciences, Beijing, China.

作者： Yan-Qiong,Zhang ^[1] ; Yan,Shen ^[2] ; Ming-Mei,Liao ^[3] ; Xia,Mao ^[1] ; Gu-Jie,Mi ^[4] ; Chen,You ^[5] ; Qiu-Yan,Guo ^[1] ; Wei-Jie,Li ^[1] ; Xiao-Yue,Wang ^[1] ; Na,Lin ^[6] ; Thomas J,Webster ^[7]

作者单位： Institute of Chinese Materials Medical, China Academy of Chinese Medical Sciences, Beijing, China. ^[1] Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China. ^[2] Key Laboratory of Nanobiological Technology of Chinese Ministry of Health, Xiangya Hospital, Central South University, Changsha, Hunan, China. ^[3] Department of Chemical Engineering, Northeastern University, Boston, USA. ^[4] Jiangsu Provincial Xuzhou Pharmaceutical Vocational College, Xuzhou, China. ^[5] Institute of Chinese Materials Medical, China Academy of Chinese Medical Sciences, Beijing, China. Electronic address: nlin@icmm.ac.cn. ^[6] Department of Chemical Engineering, Northeastern University, Boston, USA. Electronic address: th.webster@neu.edu. ^[7]

医学主题词动物(Animals);抗肿瘤药, 烷基化(Antineoplastic Agents, Alkylating);细胞凋亡(Apoptosis);癌, 肝细胞(Carcinoma, Hepatocellular);细胞增殖(Cell Proliferation);壳聚糖(Chitosan);二萜类(Diterpenes);环氧化合物(Epoxy Compounds);半乳糖(Galactose);人类(Humans);肝肿瘤(Liver Neoplasms);男(雄)性(Male);小鼠(Mice);小鼠, 裸(Mice, Nude);纳米粒子(Nanoparticles);菲类(Phenanthrenes);生殖(Reproduction);信号传导(Signal Transduction);组织分布(Tissue Distribution);肿瘤细胞, 培养的(Tumor Cells, Cultured);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.1016/j.nano.2018.09.002

PMID 30244085

发布时间 2019-02-15

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Galactosylated chitosan triptolide nanoparticles for overcoming hepatocellular carcinoma: Enhanced therapeutic efficacy, low toxicity, and validated network regulatory mechanisms.

Nanomedicine

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Galactosylated chitosan triptolide nanoparticles for overcoming hepatocellular carcinoma: Enhanced therapeutic efficacy, low toxicity, and validated network regulatory mechanisms.

Nanomedicine

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同项目论文

Nanomedicine

相关期刊

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