换一批Chloroquine enhances the cytotoxicity of cis-diamminedichloroplatinum II.
摘要：
A low dose (10 microM) of the antitumor drug cis-diamminedichloroplatinum II (cDDP) was not found to be cytotoxic to HeLa S3 cells in culture in this study, as observed by Roberts and Fraval (1978). The cytotoxicity of this nontoxic dose of cDDP, can be greatly enhanced by treating cells with 200 microMs chloroquine immediately after exposure to the platimum drug.
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作者：
S A,Quarless [1]
作者单位：
Department of Biology
[1]
Massachusetts Institute of Technology
[2]
Cambridge 02139.
[3]
主题词：
细胞存活(Cell Survival);氯喹(Chloroquine);顺铂(Cisplatin);培养技术(Culture Techniques);药物协同作用(Drug Synergism);人类(Humans)
PMID：
3224330
发布时间：
2013-11-21
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