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Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9-Cas12a platform.

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第一作者： Thomas,Gonatopoulos-Pournatzis

第一单位： Donnelly Centre, University of Toronto, Toronto, Ontario, Canada. t.gonatopoulos@gmail.com.

作者： Thomas,Gonatopoulos-Pournatzis ^[1] ; Michael,Aregger ^[2] ; Kevin R,Brown ^[2] ; Shaghayegh,Farhangmehr ^[3] ; Ulrich,Braunschweig ^[2] ; Henry N,Ward ^[4] ; Kevin C H,Ha ^[2] ; Alexander,Weiss ^[2] ; Maximilian,Billmann ^[5] ; Tanja,Durbic ^[2] ; Chad L,Myers ^[6] ; Benjamin J,Blencowe ^[7] ; Jason,Moffat ^[8]

作者单位： Donnelly Centre, University of Toronto, Toronto, Ontario, Canada. t.gonatopoulos@gmail.com. ^[1] Donnelly Centre, University of Toronto, Toronto, Ontario, Canada. ^[2] Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.;Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. ^[3] Bioinformatics and Computational Biology Graduate Program, University of Minnesota, Minneapolis, MN, USA. ^[4] Department of Computer Science and Engineering, University of Minnesota, Minneapolis, MN, USA. ^[5] Bioinformatics and Computational Biology Graduate Program, University of Minnesota, Minneapolis, MN, USA.;Department of Computer Science and Engineering, University of Minnesota, Minneapolis, MN, USA. ^[6] Donnelly Centre, University of Toronto, Toronto, Ontario, Canada. b.blencowe@utoronto.ca.;Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. b.blencowe@utoronto.ca. ^[7] Donnelly Centre, University of Toronto, Toronto, Ontario, Canada. j.moffat@utoronto.ca.;Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. j.moffat@utoronto.ca.;Institute for Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada. j.moffat@utoronto.ca. ^[8]