Genome-scale CRISPR screening for modifiers of cellular LDL uptake.
作者:
Brian T,Emmer [1]
;
Emily J,Sherman [2]
;
Paul J,Lascuna [2]
;
Sarah E,Graham [3]
;
Cristen J,Willer [2]
;
David,Ginsburg [1]
作者单位:
Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
[1]
Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America.
[2]
Chemical Biology Program, University of Michigan, Ann Arbor, Michigan, United States of America.
[3]
Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, United States of America.
[4]
Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America.
[5]
Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, Michigan, United States of America.
[6]
Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan, United States of America.
[7]
期刊:
《PLoS genetics》
2021年17卷1期e1009285页
主题词:
动脉粥样硬化(Atherosclerosis);胆固醇(Cholesterol);胞吞作用(Endocytosis);基因表达调控(Gene Expression Regulation);基因组, 人(Genome, Human);Hep G2细胞(Hep G2 Cells);肝细胞(Hepatocytes);人类(Humans);高胆固醇血症(Hypercholesterolemia);脂蛋白类, LDL(Lipoproteins, LDL);受体, LDL(Receptors, LDL)
DOI:
10.1371/journal.pgen.1009285
PMID:
33513160
发布时间:
2024-01-04
- 翻译满意度评价:
- 提交
- 浏览:0
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文