换一批A novel method of protein analysis for prediction of biological function: application to tumor toxins.
摘要：
Informational spectra method was applied to the analysis of lymphotoxin and tumor necrosis factor. The correlation between the information contained in primary structure of these tumor toxins and some oncogen transforming proteins was established. This correlation implies the possibility of a competitive action between these two groups of proteins. "Hot spots" positions in the primary structure of lymphotoxin and tumor necrosis factor for the functional "up" and "down" mutations were predicted.
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作者：
V,Veljković ;
I,Cosić
期刊：
主题词：
氨基酸序列(Amino Acid Sequence);动物(Animals);碱基序列(Base Sequence);糖蛋白类(Glycoproteins);淋巴毒素α(Lymphotoxin-alpha);突变(Mutation);癌基因蛋白质类, 病毒性(Oncogene Proteins, Viral);蛋白质构象(Protein Conformation);蛋白质类(Proteins);软件(Software);构效关系(Structure-Activity Relationship);肿瘤坏死因子α(Tumor Necrosis Factor-alpha);水(Water)
PMID：
3497707
发布时间：
2013-11-21
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