Evidence of epoxide hydrase activity in human intestinal microflora.-论文-万方医学网

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Evidence of epoxide hydrase activity in human intestinal microflora.

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摘要：

Cholesterol-5 alpha, 6 alpha-epoxide has been implicated as an etiologic agent in human colon cancer. The epoxide is metabolized by human intestinal microflora to a product which was characterized by thin-layer and gas-liquid chromatography as well as combined gas-liquid chromatography-mass spectrometry. Chromatographic properties are identical with authentic cholestan-3 beta, 5 alpha, 6 beta-triol, and these results suggest that microbial epoxide hydrase activity is present in the human colon.

作者： K K,Hwang ; M I,Kelsey

期刊：

《Cancer biochemistry biophysics》 1978年3卷1期31-5页

主题词：胆甾烷醇类(Cholestanols);胆固醇(Cholesterol);色谱法, 薄层(Chromatography, Thin Layer);结肠(Colon);肠杆菌科(Enterobacteriaceae);环氧水解酶类(Epoxide Hydrolases);粪便(Feces);气相色谱-质谱法(Gas Chromatography-Mass Spectrometry);人类(Humans)

PMID： 552896

发布时间： 2013-11-21

翻译满意度评价：: 准确一般字义偏差语意偏离译文作用小提交

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