换一批Subcellular distribution of spin-labeled bithiazoles and bleomycin in living KB cells: an ESR study.
摘要：
Spin-labeled derivatives of bithiazole and bleomycin were studied with respect to their uptake and localization in KB cells in vivo. It was found that the amidification of the C-terminal carboxylic group of bleomycinic acid was essential for the penetration of the probes in the cells and that the subcellular localization depended on the number and spacing of positively charged groups.
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作者：
J P,Henichart ;
J L,Bernier ;
P,Lemay ;
R,Houssin ;
J P,Catteau
期刊：
主题词：
博来霉素(Bleomycin);细胞核(Cell Nucleus);环氮氧化物(Cyclic N-Oxides);细胞质(Cytoplasm);电子自旋共振谱学(Electron Spin Resonance Spectroscopy);人类(Humans);KB细胞(KB Cells);自旋标记物(Spin Labels);噻唑类(Thiazoles)
PMID：
6207910
发布时间：
2006-11-15
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