Conditions for the generation of high serum levels of C3DP.-论文-万方医学网

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Conditions for the generation of high serum levels of C3DP.

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摘要：

High titers of C3DP, a DNA-binding derivative of complement C3, have been reported to occur in the sera of individuals with active malignant disease. The mechanism of generation of C3DP remained obscure. We report here that C3DP is not generated in vitro under the conditions required for its isolation and subsequent assay. However, under certain storage conditions, all sera (normal and malignant) produce C3DP. This severely limits the usefulness of the assay for diagnostic and prognostic purposes.

作者： P J,White ; S O,Hoch

期刊：

《Cancer biochemistry biophysics》 1982年6卷1期19-22页

主题词：血液(Blood);血液保存(Blood Preservation);载体蛋白质类(Carrier Proteins);色谱法, 亲和(Chromatography, Affinity);DNA结合蛋白质类(DNA-Binding Proteins);假阳性反应(False Positive Reactions);人类(Humans);肿瘤蛋白质类(Neoplasm Proteins);肿瘤(Neoplasms);放射免疫测定(Radioimmunoassay)

PMID： 7093934

发布时间： 2007-11-14

翻译满意度评价：: 准确一般字义偏差语意偏离译文作用小提交

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