The PEST-like sequence of I kappa B alpha is responsible for inhibition of DNA binding but not for cytoplasmic retention of c-Rel or RelA homodimers.
第一作者:
M K,Ernst
第一单位:
Laboratory of Molecular Virology and Carcinogenesis, National Cancer Institute Frederick Cancer Research and Development Center, Maryland 21702-1201.
作者:
主题词
氨基酸序列(Amino Acid Sequence);动物(Animals);碱基序列(Base Sequence);细胞系(Cell Line);共有序列(Consensus Sequence);DNA结合蛋白质类(DNA-Binding Proteins);人类(Humans);I-κB蛋白质类(I-kappa B Proteins);大分子物质(Macromolecular Substances);小鼠(Mice);分子序列数据(Molecular Sequence Data);诱变, 定点(Mutagenesis, Site-Directed);NF-κB(NF-kappa B);寡脱氧核糖核苷酸类(Oligodeoxyribonucleotides);原癌基因蛋白质类(Proto-Oncogene Proteins);原癌基因蛋白质c-rel(Proto-Oncogene Proteins c-rel);转录因子RelA(Transcription Factor RelA);转录因子(Transcription Factors);转染(Transfection)
DOI
10.1128/MCB.15.2.872
PMID
7823953
发布时间
2021-05-26
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