换一批Serum N-acetyl-beta-glucosaminidase activity in breast cancer.
摘要：
N-acetyl-beta-glucosaminidase (NAG) and its isoenzymes were measured in 60 patients with breast cancer and in 30 patients suffering from benign breast tumors. NAG activity was significantly increased (P < 0.001) in cancer patients. The concentration of isoenzyme A always exceeded that of isoenzyme B, but isoenzyme B concentration was significantly (p < 0.001) higher in patients than in controls. An intermediate form, I, was more evident but not significant in patients. Evaluation of the predictive value of the NAG isoenzyme B, revealed a good sensitivity, efficiency and specificity. It seems from this study that the determination of the isoenzyme NAG B activity may be useful for better diagnosis of breast cancer.
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作者：
G,Severini [1]
;
L M,Aliberti [2]
作者单位：
Lab. Biochimica Clinica
[1]
Instituto Superiore di Sanità
[2]
Roma
[3]
Italia.
[4]
期刊：
主题词：
乙酰氨基葡糖苷酶(Acetylglucosaminidase);乳腺疾病(Breast Diseases);乳腺肿瘤(Breast Neoplasms);人类(Humans);同工酶类(Isoenzymes);肿瘤蛋白质类(Neoplasm Proteins);试验预期值(Predictive Value of Tests);敏感性与特异性(Sensitivity and Specificity)
PMID：
7889495
发布时间：
2015-11-19
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