Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA.
第一作者:
M D,Weitzman
第一单位:
Laboratory of Molecular and Cellular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 20892.
作者:
主题词
细菌蛋白质类(Bacterial Proteins);碱基序列(Base Sequence);结合部位(Binding Sites);结合, 竞争性(Binding, Competitive);染色体, 人, 19对(Chromosomes, Human, Pair 19);克隆, 分子(Cloning, Molecular);DNA(DNA);DNA解旋酶类(DNA Helicases);DNA, 病毒(DNA, Viral);DNA结合蛋白质类(DNA-Binding Proteins);依赖病毒(Dependovirus);基因组, 病毒(Genome, Viral);人类(Humans);甲基化(Methylation);模型, 结构(Models, Structural);分子序列数据(Molecular Sequence Data);核酸构象(Nucleic Acid Conformation);寡脱氧核糖核苷酸类(Oligodeoxyribonucleotides);重组蛋白质类(Recombinant Proteins);反式激活因子类(Trans-Activators);病毒整合(Virus Integration)
DOI
10.1073/pnas.91.13.5808
PMID
8016070
发布时间
2021-08-30
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