A dominant-negative mutant of raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21ras.
第一作者:
D,Schaap
第一单位:
Division of Cellular Biochemistry, The Netherlands Cancer Institute, Amsterdam.
作者:
主题词
氨基酸序列(Amino Acid Sequence);动物(Animals);抗体, 单克隆(Antibodies, Monoclonal);钙-钙调素依赖性蛋白激酶类(Calcium-Calmodulin-Dependent Protein Kinases);细胞系(Cell Line);二酰甘油激酶(Diacylglycerol Kinase);酶激活(Enzyme Activation);表皮生长因子(Epidermal Growth Factor);基因, myc(Genes, myc);人类(Humans);同工酶类(Isoenzymes);小鼠(Mice);分子序列数据(Molecular Sequence Data);诱变(Mutagenesis);寡肽类(Oligopeptides);佛波醇12,13-二丁酸盐(Phorbol 12,13-Dibutyrate);磷酸转移酶类(Phosphotransferases);蛋白激酶C(Protein Kinase C);蛋白激酶类(Protein Kinases);蛋白酪氨酸激酶类(Protein-Tyrosine Kinases);蛋白质类(Proteins);原癌基因蛋白质类(Proto-Oncogene Proteins);原癌基因蛋白质c-raf(Proto-Oncogene Proteins c-raf);原癌基因蛋白质类p21(ras)(Proto-Oncogene Proteins p21(ras));原癌基因(Proto-Oncogenes);重组蛋白质类(Recombinant Proteins);序列缺失(Sequence Deletion);转染(Transfection)
PMID
8397201
发布时间
2021-02-10
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