Calpain cleavage of focal adhesion proteins regulates the cytoskeletal attachment of integrin alphaIIbbeta3 (platelet glycoprotein IIb/IIIa) and the cellular retraction of fibrin clots.
第一作者:
S M,Schoenwaelder
第一单位:
Department of Medicine, Monash Medical School, Box Hill Hospital, Arnold Street, Box Hill, Victoria, Australia 3128.
作者:
主题词
血小板(Blood Platelets);卡配因(Calpain);细胞骨架(Cytoskeleton);酶激活(Enzyme Activation);纤维蛋白(Fibrin);人类(Humans);水解作用(Hydrolysis);血小板活化(Platelet Activation);血小板糖蛋白GPⅡb-Ⅲa复合物(Platelet Glycoprotein GPIIb-IIIa Complex);蛋白质结合(Protein Binding);原癌基因蛋白质类pp60(c-src)(Proto-Oncogene Proteins pp60(c-src))
DOI
10.1074/jbc.272.3.1694
PMID
8999848
发布时间
2021-02-09
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