Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders.
第一作者:
L G,Presta
第一单位:
Department of Immunology, Genentech, Inc., South San Francisco, California 94080, USA.
作者:
主题词
肾上腺皮质(Adrenal Cortex);氨基酸序列(Amino Acid Sequence);动物(Animals);抗体, 单克隆(Antibodies, Monoclonal);毛细血管(Capillaries);牛(Cattle);细胞, 培养的(Cells, Cultured);克隆, 分子(Cloning, Molecular);共有序列(Consensus Sequence);内皮生长因子类(Endothelial Growth Factors);内皮, 血管(Endothelium, Vascular);女(雌)性(Female);人类(Humans);免疫球蛋白Fab片段(Immunoglobulin Fab Fragments);免疫球蛋白G(Immunoglobulin G);免疫球蛋白重链(Immunoglobulin Heavy Chains);免疫球蛋白轻链(Immunoglobulin Light Chains);免疫球蛋白可变区(Immunoglobulin Variable Region);淋巴因子(Lymphokines);小鼠(Mice);小鼠, 裸(Mice, Nude);模型, 结构(Models, Structural);分子序列数据(Molecular Sequence Data);新生血管化, 病理性(Neovascularization, Pathologic);蛋白质构象(Protein Conformation);大鼠(Rats);重组融合蛋白质类(Recombinant Fusion Proteins);横纹肌肉瘤(Rhabdomyosarcoma);序列比对(Sequence Alignment);移植, 异种(Transplantation, Heterologous);肿瘤细胞, 培养的(Tumor Cells, Cultured);血管内皮生长因子A(Vascular Endothelial Growth Factor A);血管内皮生长因子类(Vascular Endothelial Growth Factors)
PMID
9377574
发布时间
2022-04-09
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Cancer research
4593-9页
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