Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway.
第一作者:
J R,Kennerdell
第一单位:
Department of Biological Sciences, University of Pittsburgh, Pennsylvania 15260, USA.
作者:
医学主题词
动物(Animals);细菌蛋白质类(Bacterial Proteins);躯体发育模式(Body Patterning);果蝇蛋白质类(Drosophila Proteins);黑腹果蝇(Drosophila melanogaster);上位性, 遗传(Epistasis, Genetic);Frizzled受体(Frizzled Receptors);fushi tarazu转录因子类(Fushi Tarazu Transcription Factors);糖原合成酶激酶3(Glycogen Synthase Kinase 3);同源盒结构域蛋白质类(Homeodomain Proteins);免疫组织化学(Immunohistochemistry);注射(Injections);昆虫蛋白质类(Insect Proteins);膜蛋白质类(Membrane Proteins);核酸杂交(Nucleic Acid Hybridization);表型(Phenotype);原癌基因蛋白质类(Proto-Oncogene Proteins);RNA, 反义(RNA, Antisense);RNA, 双链(RNA, Double-Stranded);受体, 细胞表面(Receptors, Cell Surface);受体, G-蛋白偶联(Receptors, G-Protein-Coupled);受体, 神经递质(Receptors, Neurotransmitter);阻遏蛋白质类(Repressor Proteins);信号传导(Signal Transduction);转录因子(Transcription Factors);Wnt1蛋白质(Wnt1 Protein)
DOI
10.1016/s0092-8674(00)81725-0
PMID
9875855
发布时间
2021-12-03
- 浏览147
Cell
1017-26页
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