Th17/Treg在毛细支气管炎发病机制中的作用
Advancement of Thl7/Treg in children with bronchiolitis
毛细支气管炎是2岁以下婴幼儿最常见的下呼吸道感染性疾病之一,主要病原体是呼吸道合胞病毒,且与哮喘的发病密切相关.毛细支气管炎的发病机制至今尚未完全阐明,近年来发现辅助性T细胞l7(Thl7)和调节性T细胞(Treg)的失衡在其发病中占有重要地位.该文就近年来对Thl7/Treg失衡在毛细支气管炎发病机制方面的研究进展作一综述.
更多Bronchiolitis is a common lower respiratory infectious disease in children under two years old.The main pathogen of bronchiolitis is respiratory syncytial virus.Bronchiolitis is also associated with asth-ma.It is still unknown for us about the pathogenesis of bronchiolitis.In recent years,we were found find that the T helper l7 cell(Thl7)and regulatory T cell(Treg)play an important role in bronchiolitis.We review the role of Thl7/Treg imbalances in the pathogenesis of bronchiolitis in this paper.
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