换一批摘要核因子κB(nuclear factor-κB,NF-κB)是调控多种基因表达的核转录因子,其活化失调不仅与各种炎症性疾病有关,而且在肺癌的发生、发展、转移及治疗中也发挥着重要的作用.近年来研究发现,NF-κB可能是抗癌药物治疗的靶点,为肺癌等恶性肿瘤的治疗提供了新思路.
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abstractsNuclear factor-κB (NF-κB) is a nuclear transcription factor that regulates expression of diverse genes.Its activation disproportion is not only involved in a variety of inflammatory diseases,but also plays an important role in the development,progress,metastasis,and treatment of lung cancer.Recently,some studies have found that NF-κB may be a target for anti-cancer drugs,providing a new idea for the treatment of lung cancer and other malignant tumors.
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栏目名称
DOI
10.3760/cma.j.issn.1673-436X.2013.018.011
发布时间
2013-10-31（万方平台首次上网日期，不代表论文的发表时间）
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