国产药物涂层支架用于CABG术后冠状动脉再次血管重建及1年随访结果分析
One-year clinical outcomes in patients with previous coronary artery bypass graft surgery treated by using percutaneous revascularization with domestically made drug-eluting stent
目的 评估国产药物涂层支架( drug-eluting stent,DES)治疗冠状动脉旁路移植术(coronary artery bypass graft,CABG)后心肌缺血患者的疗效,明确相关因素对植入国产DES术后主要心脑血管不良事件(major adverse cardiovascular and cerebral events,MACCE)发生率的影响。方法 入选2008年9月至2009年10月于北京安贞医院接受国产DES治疗的CABG术后病例83例,随访1年,观察国产DES植入治疗CABG术后心肌缺血患者的疗效,并利用Logistic回归分析相关因素与MACCE的相关性。结果 国产DES植入手术成功率97.5%,随访结果显示10例患者发生MACCE (12.0%),其中死亡1例(1.2%),缺血性脑中风l例(1.2%),心肌梗死l例(1.2%),再次血管重建8例(9.6%),靶病变重建l例(1.2%)。结论 国产DES植入治疗CABG后心肌缺血患者安全,近中期疗效良好,血栓发生率低。罪犯血管完全血管重建是MACCE的独立预测因子。
更多Objective To evaluate the immediate and 1-year outcomes of percutaneous coronary intervention (PCI) with domestically made drug-eluting stent (DES) in patients with previous coronary bypass graft surgery (post-CABG) in order to determine the relationship between related factors and major adverse cardiovascular and cerebral events (MACCE) after PCI. Methods From September 2008 to October 2009, 83 consecutive post-CABG patients had implantation of 176 domestically made DES for 126 coronary lesions. Each patient was followed up at least for 1 year after the procedure done for the evaluation of the efficacy and safety of DES implanted in post-CABG patients. Logistic regression analysis was used to determine the relationship between major factors and MACCE. Results The success rate of operation procedure was 97. 5%. MACCE occurred in 10 patients including death in 1 patient, stroke in 1 patient,myocardial infarction in 1 patient, and those were treated with repeated coronary revascularization in 8patients and target lesion revascularization (TLR) in 1 patient. Conclusions Immediate and medium-term results showed the safety and efficacy of revascularization with domestically made DES in post-CABG patients. Complete revascularization was an independent predictor of MACCE.
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