摘要方法　维生素D缺乏在孕妇和新生儿中较为普遍，其对新生儿肺发育有重要作用。动物实验显示维生素D对肺泡Ⅱ型细胞、成纤维细胞增殖，表面活性物质合成和肺泡化有显著积极作用。临床研究显示维生素D缺乏新生儿需要辅助通气，呼吸窘迫综合征(RDS)及支气管肺发育不良(BPD)的比例较高，需氧时间更长。基于此，现系统地回顾了维生素D对肺发育、表面活性物质合成、RDS和BPD的影响。

abstractsVitamin D deficiency is common among pregnant women and newborns, and Vitamin D plays an important role in the neonatal lung development.Animal experiments proved that Vitamin D has a significant effect on type Ⅱ alveolar cell proliferation, fibroblast proliferation, surfactant synthesis and alveolarization.Clinical studies revealed that there is a higher proportion of assisted ventilation, respiratory distress syndrome(RDS)and bronchopulmonary dysplasia(BPD), and longer aerobic duration in neonates with Vitamin D deficiency.Therefore, this article systematically reviewed the effects of Vitamin D on lung development, surfactant synthesis, RDS, and BPD.