社会支持与化疗期肺癌患者胃肠道反应的相关性研究
Study on the relationship between social support and gastrointestinal reaction in patients with lung cancer during chemotherapy
目的:探讨社会支持与化疗期肺癌患者胃肠道反应的相关性,为临床干预性研究提供科学依据。方法对120例化疗期肺癌患者分别用一般情况调查表、社会支持评定量表、胃肠道反应评估表进行调查,并对结果进行分析。结果社会支持总分及其3个维度与化疗期肺癌患者胃肠道反应呈负相关(r=-0.520~-0.168),除支持利用度与腹泻相关性无统计学意义(r=-0.168, P>0.05)外,其余均有统计学意义(P<0.05或0.01);多元逐步回归分析发现:主观支持及社会支持总分对化疗期肺癌患者胃肠道反应预测有统计学意义(P<0.05),分别可解释相应胃肠道反应的12.4%~27.0%的变异,对其影响均为负向。结论社会支持与化疗期肺癌患者胃肠道反应密切相关,良好的社会支持有助于减轻患者的胃肠道反应。
更多Objective To investigate the correlation between social support and gastrointestinal reaction in chemotherapy patients with lung cancer in order to provide scientific evidence for clinical intervention. Methods A total of 120 cases of lung cancer patients receiving chemotherapy were investigated by the general questionnaire, Social Support Rating Scale and gastrointestinal reaction assessment form. The results were analyzed. Results Total score of social support and its 3 dimensions were negatively related to gastrointestinal reactions in chemotherapy patients with lung cancer (r=-0.520--0.168),and all had statistical significance (P<0.05 or 0.01) except the utilization of support and diarrhea (r=-0.168, P>0.05). Multivariate stepwise regression analysis showed that the predictions of subjective support and total score of social support on gastrointestinal reaction were statistically significant (P < 0.05), which can explain the variation of 12.4%-27.0%of the gastrointestinal reaction, and the effect was negative. Conclusions The social support is closely related to the gastrointestinal reaction in chemotherapy patients with lung cancer, and good social support can help to reduce gastrointestinal reaction.
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