检索历史 清除

目的 系统检索危重患儿肠内喂养方案相关研究,并提取喂养方案中相关元素.方法 以危重患儿、肠内营养支持流程、肠内营养实践等为关键词,检索BIOSIS Previews、PubMed、MEDLINE、EMbase、中国生物医学文献数据库、中国知网和万方数据资源系统2016年1月31日前相关文献.提取纳入文章基本信息、喂养元素、喂养效果评价指标、喂养方案主导者、喂养方案制定方法等数据.结果 纳入3份历史对照研究,3份非同期对照,2份队列研究,1份综述和1份质性研究,共10份喂养方案.从中提取营养评估、预估能量、推进速度、喂养不耐受等16个喂养元素.其中所有方案均规定喂养推进速度及喂养不耐受界值.结论 多数危重症监护室应用肠内喂养方案改善患儿营养状况,但无统一标准,部分喂养元素缺乏证据支持,仍需大量研究进一步探讨.

Objective To conduct a scoping review to systematically review the literature reporting enteral feeding protocol in critical ill children. And extract elements of enteral feeding protocol. Methods The database of BIOSIS Previews, PubMed, MEDLINE, EMbase, China Biology Medicine Disc, China National Knowledge Infrastructure and Wan Fang data were searched. Data were extracted on the information of article, elements of enteral feeding, evaluation of feeding etc. Results Three historical controlled studies, three case-control studies, two cohort studies, one narrative review and one qualitative study were included. Totally 16 elements were got, such as nutrition evaluation, estimated energy requirement, contraindication, feeding intolerance etc. And all protocols defined advancement and feeding intolerance. Conclusions Enteral feeding protocol has been used in most PICUs to optimize nutrition. But we observed variability in the composition of protocols and lack of evidence-based recommendations in few elements.