脑机接口训练对脑卒中患者肢体功能障碍干预效果的Meta分析
Effects of brain-computer interface on disturbance of extremity function in stroke patients: a Meta-analysis
目的:系统评价脑机接口训练对脑卒中患者肢体功能障碍的干预效果。方法:检索Cochrane、EBSCO、PubMed、EMbase、Web of Science、JBI、MEDLINE、RNAO、Nursing Consult、CINAHL、中国知网、万方和维普数据库中脑机接口训练对脑卒中患者干预研究的随机对照试验,由2名研究者进行质量评价并提取数据后,采用RevMan5.3软件分析。结果:共纳入12项随机对照试验研究,研究对象347例。脑机接口训练能够改善脑卒中患者肢体运动[均数差( MD)为5.00,95%可信区间(95% CI)3.50~6.49, Z值为6.55, P<0.01]与上肢动作功能( MD值为9.66,95% CI 3.74~15.59, Z值为3.20, P<0.01),提高肌力( SMD值为0.91,95% CI 0.49~1.32, Z值为4.23, P<0.01)与日常生活活动能力( SMD值为0.84,95% CI 0.42~1.26, Z值为3.89, P<0.01),但对肌痉挛无明显作用( MD值为-0.08,95% CI-0.47~0.31, Z值为0.39, P>0.05)。 结论:脑机接口训练能够改善脑卒中患者肢体运动功能、动作、肌力和日常生活活动能力,但对肌痉挛的作用不明显。
更多Objective:To evaluate the effects of brain-computer interface training on extremity function for stroke patients.Methods:Cochrane, EBSCO, PubMed, EMbase, Web of Science, JBI, MEDLINE, RNAO, Nursing Consult, CINAHL, CNKI, WanFang and VIP were searched to collect randomized controlled trials of brain-computer interface training on stroke patients, after quality evaluation and data extraction by two researchers, statistical processing was performed by RevMan5.3 software.Results:Twelve randomized controlled trials and 347 patients were included. The results showed that brain-computer interface training could improve the patients' limb motor function (mean difference value was 5.00, 95% confidence interval was 3.50-6.49, Z value was 6.55, P<0.01) and upper limb action function (mean difference value was 9.66, 95% confidence interval was 3.74-15.59, Z value was 3.20, P<0.01), enhanced the myodynamia (standardized mean difference was 0.91, 95% confidence interval was 0.49-1.32, Z value was 4.23, P<0.01) and activities of daily living (standardized mean difference was 0.84, 95% confidence interval was 0.42-1.26, Z value was 3.89, P<0.01], but had no significant effect on myospasm (mean difference value was -0.08, 95% confidence interval was -0.47-0.31, Z value was 0.39, P>0.05). Conclusions:Brain-computer interface training can improve limb motor function, action, myodynamia and activities of daily living for stroke patients, but have no significant effect on myospasm.
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