抑郁对胃癌患者化疗依从性的影响
Effects of depression on the compliance of chemotherapy in stomach cancer patients
目的:探讨抑郁对胃癌患者化疗依从性的影响。方法选择2013年1月—2014年6月收治的100例接受化疗治疗的胃癌患者,采用Zung抑郁自评量表( SDS)对患者的抑郁状况进行评估,并采用化疗依从性量表对患者抑郁与化疗相关性进行分析,并对患者化疗依从性进行评估。结果100例患者SDS平均得分为(57.24±4.76)分,抑郁症患者占53%,其中轻度抑郁24例,中度抑郁16例,重度抑郁13例。无抑郁组患者中57.4%化疗依从性好,仅有17.1%的患者依从性较差;抑郁组患者中28.3%化疗依从性好,有30.2%的患者不依从,两组依从性比较,差异有统计学意义( Z=2.742,P<0.05)。结论抑郁能够降低胃癌患者化疗依从性,使患者生存及生活质量降低,病情加重。
更多Objective To explore depression impacted on chemotherapy compliance in patients with stomach cancer. Methods A total of 100 stomach cancer patients, who received chemotherapy treatment in our hospital from January 2013 to June 2014, were selected and evaluated patients′ depression condition by Zung self-depression scale. The chemotherapy compliance was evaluated in patients as well. Results The average score of SDS was (57. 24 ± 4. 76) in 100 patients, depressed patients occupying 53% within which 24 cases had light depression, 16 cases moderate depression and 13 cases with severe depression. 57. 4% non-depressed patients had excellent chemotherapy compliance, and only 17. 1% of them had poor compliance; 28. 3%depressed patients had excellent chemotherapy compliance, and only 30. 2% of them had no compliance ( Z=2. 742,P<0. 05). Conclusions Depression can decrease chemotherapy compliance in patients with stomach cancer, which leads to reduce survival of life, and deteriorate disease.
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