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目的? 探讨不同间歇式充气加压泵(IPC)应用时间对重症脑卒中患者下肢DVT形成的预防效果.方法? 2017年9月—2018年8月,采用便利抽样法,选择首都医科大学宣武医院神经内科监护室脑卒中患者154例为研究对象.2017年9月—2018年2月住院的77例患者为对照组,2018年3—8月住院的77例患者为干预组.对照组患者使用IPC频次为每日2次,每次1 h;干预组患者使用间歇式充气压力泵为每日12 h连续使用.比较两组患者DVT发生率和发生时间.结果? 干预组发生DVT 20例(26.0%),对照组22例(28.6%),两组患者下肢DVT发生率差异无统计学意义(χ2=0.131,P＞0.05);干预组DVT发生时间中位数为9.00 d,对照组血栓发生时间中位数3.50 d,两组DVT发生时间差异有统计学意义(Z=-2.344,P＜0.05).结论? 对于重症脑卒中患者延长间歇式充气压力泵使用时间虽然不能降低DVT发生,但可有效延迟DVT的发生时间.

Objective? To explore the preventive effects of different application time of intermittent pneumatic compression devices (IPC) on deep vein thrombosis (DVT) of lower extremities in patients with severe stroke. Methods? Totally 154 stroke patients from the Neurological Intensive Care Unit, Xuanwu Hospital, Capital Medical University were selected by convenient sampling from September 2017 to August 2018. Totally 77 patients admitted from September 2017 to February 2018 were included into the control group, while another 77 patients admitted from March to August 2018 were included into the intervention group. IPC was applied to patients in the control group twice a day and for 1 h each time, while it was applied to patients in the intervention group consecutively for 12 h each day. The incidence rate and time of DVT was compared between the two groups. Results? A total of 20 (26.0%) cases with DVT were found in the intervention group, while 22 (28.6%) cases were found in the control group, and there was no statistically significant difference in the incidence rate of DVT between the two groups (χ2=0.131, P＞0.05). The median incidence time of DVT in the intervention group was 9.00 d, while that in the control group was 3.50 d, and there was statistically significant difference in the incidence time of DVT between the two groups (Z=-2.344, P＜0.05). Conclusions? Prolonged use of IPC in patients with severe stroke may delay the incidence time of DVT, though it cannot reduce its incidence rate.