努力提高胰腺癌手术切除率
Strive to improve the resection rate of pancreatic cancer
With the increasing incidence and high malignancy, pancreatic cancer is still expected to be treated by radical resection. However, because of the unique anatomical and biological features, such as rapid progression, early metas-tasis and direct invasion to the vessels, the resection rate of pan-creatic cancer is still at a lower level. The standard procedures of diagnosis and treatment, including early detection, preopera-tive resectability assessment, and judgement of the resection area based on the tumor staging, benefit the patients and significantly improve the prognosis.
更多@@ 胰腺癌是一种常见的消化道肿瘤.其发病率在全球范围内呈上升趋势,不仅在西方国家已成为10种常见的恶性肿瘤之一,在国内近20年来的发病率也增加了1~5倍,发病率和病死率分别从20世纪60年代的第22位和第15位上升至20世纪90年代的第5位和第6位,占男性死因的第6~8位,女性死因的第9~10位<'[1-2]>.同时,胰腺癌恶性程度极高,且位置深在、发病隐匿、发展迅速、早期转移、直接侵犯血管.约85%的患者发现时已属于Ⅲ、Ⅳ期,中位生存时间不足6个月,5年总体生存率低于5%,年发病率与年病死率几乎相等<'[1]>.目前外科治疗是胰腺癌综合治疗方案中最重要、最有效的一个环节,根治性手术是有望治愈胰腺癌的惟一手段.者预后的关键因素.
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