检索历史 清除

The incidence of rectal cancer has been increasing over past decades in China, making it the third most common malignant tumor. Multidisciplinary treatment plays a fundamental role in the successful treatment of rectal cancer.Total mesorectal excision has been wildly accepted as the standard technique, however, this procedure has not been standardized in China. Neoadjuvant radiation has been accepted as a standard regimen for patients with an advanced rectal cancer at a higher risk of local recurrence, even though controversies remain, such as the selection of patients for preoperative radiation and the optimum regimen for radiation. Combination of chemotherapeutic agents and targeted therapies is recommended according to updated results of randomized controlled trials (RCTs). In the future, multidisciplinary treatment should be adjusted according to the socioeconomic status of China and RCTs results in Chinese population. Standardization of surgery and surgery quality control also continue to play a core role in improving treatment results of rectal cancer in China.

@@ 近10余年来,多学科综合治疗已逐步成为直肠癌治疗的基本原则.直肠癌外科手术的规范及优化,围手术期放、化疗的应用,使直肠癌患者术后生命质量有了显著地提高.但多学科综合治疗中的新辅助治疗适用的范围、方案的选用、治疗效果等方面仍存在争议.只有对多学科综合治疗的具体规范进行优化和调整,制定适合我国国情的直肠癌多学科综合治疗规范,才能让患者得到最合理的治疗,减少医疗的随意性,同时避免医疗资源的浪费.